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Targeting mitochondrial protection and repair represents a promising strategy to improve long-term outcomes in people living with HIV

Similar protective effects were observed with DFO (Fig

doi: 10.1007/s11695-025-08120-z Jia Yi Tan , Yong Hao Yeo , Hermon Kha Kin Wong , Shatha Elemian , Marwa Mir , Qi Xuan Ang , Arya Mariam Roy , Daniel Ezekwudo , Hamid S Shaaban

Fas is a member of the death receptor family that induces apoptosis through binding to the Fas ligand

These effects may be magnified in individuals with chronic diseases that have an inflammatory component (e.g., obesity, diabetes, heart disease), as well as in those with age-related, low-grade inflammation, also known as inflammaging