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2020 Available from: 73

TB-500 is a synthetic fragment used in research to study pathways related to Thymosin Beta-4

Another detailed aspect of combination therapy involves the use of TGF- inhibitors alongside agents targeting other key signaling pathways implicated in fibrosis, such as the Wnt/-catenin or PI3K/Akt pathways (128)

Expression of Fas and FasL depends on the stage of erythropoiesis, which allows regulating expansion of cells via inducing apoptosis of Fas-expressing immature erythroblasts by FasL-expressing mature erythroblasts [98]

Since ED is a common comorbidity in this group and patients often avoid reporting it actively due to a sense of shame, all male patients with genital involvement, high disease activity, or subjective reports of decreased QoL should be included in the systematic assessment