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Finally, we give recommendations for a rational development of transporter-utilizing drug delivery systems targeting the brain based on CNS pharmacokinetic principles

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Instead, FR- is mostly expressed on healthy epithelial cells and is overexpressed in cancerous tissues made of the same cell types

Pawlik M, Czarnecka AM, Koodziej M, Skowroska K, Wgrzynowicz M, Podgajna M, Czuczwar SJ, Albrecht J (2023) Attenuation of initial pilocarpine-induced electrographic seizures by methionine sulfoximine pretreatment tightly correlates with the reduction of extracellular taurine in the hippocampus