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Factor Xa Factor Xa is a serine protease that specifically cleaves a sequence I(E/D) GRX, where X can be any amino acid except arginine or proline, enabling removal of N-terminal affinity tags with minimal residual amino acids at the target proteins N-terminus [139]

7 and Supplementary Tables 4 and 512)

According to the American Academy of Sleep Medicine, lack of sleep speeds up biological aging since it boosts the molecular process involved in growing older