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10.3390/ijms18020423 Int

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Furthermore, there was an increase in the microphage activation marker Iba-1 in the spinal cord, suggesting that phagocytosis occurred in response to myelin debris production [82]

In separate Phase 2 and Phase 3 trials, retatrutide at 12mg produced greater total body weight reduction than semaglutide at 2.4mg across comparable timeframes, with the difference primarily attributable to retatrutides additional glucagon receptor activation