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*-OHdG is widely used as a marker of oxidative stress and other degenerative conditions

To view a copy of this licence, visit About this article Cite this article Rhee, C.K., Lim, S.Y., Lee, WY

doi: 10.1152/ajplung.00447.2017

Exercise activates adipose Ppar, which binds the Peroxisome Proliferator Response Element (PPRE) in the Nrg4 promoter to drive Nrg4 transcription

They act to increase the basal metabolic rate, affect protein synthesis, help regulate long bone growth (synergy with growth hormone) and neural maturation, and increase the body's sensitivity to catecholamines (such as norepinephrine and epinephrine) by permissiveness, especially under cold exposure