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Biomaterials 232:119752

Impaired mitochondrial function results in the release of more ROS, which activates pro-apoptotic protein production, culminating in nerve cell apoptosis (Saito et al., 2021)

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4 However, if patient exhibited more than mild hepatic dysfunction, reduced cyclophosphamide dosing should be considered

The tumor microenvironment is known for its pivotal role in immune evasion, with tumor-associated macrophages, myeloid-derived suppressor cells, and regulatory T cells creating an immunosuppressive niche that sustains GBM growth