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In non-enzymatic lipid peroxidation, when initial PLOOH (phospholipid hydroperoxides) are generated and not promptly reduced by the enzyme GPX4, they can react with ferrous ions, leading to the generation of alkoxyl and peroxyl radicals through the Fenton reaction

(see Table 1 for more details)

If more doctors were aware of how melatonin works with blood pressure, there would be fewer prescriptions for blood pressure medications and many more for melatonin supplementation

Villa-Bellosta, R., Wang, X., Millan, J

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