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Content and images used with permission from the Journal of Drugs in Dermatology

Ferroptosis can exacerbate mitochondrial oxidative stress through the NRF2-ARE pathway ( MiR-23a-3p targets and regulates SLC7A11, promoting oxidative stress and ferroptosis, which contribute to the progression of AF ( GPX4 is a critical antioxidant enzyme that inhibits lipid peroxidation and reduces ROS accumulation (Thomas et al., 1990)

A.PawlukH.Bloch-BoguslawskaE.SliwkaK

Solution : To minimize cross-reactivity, researchers should use high-quality reagents and optimize assay conditions to reduce non-specific interactions

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