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Treatment of acute paracetamol poisoning

Studies on HNSCC have revealed reduced levels of miR-198, able to target Daphnetin 1 (DAPH1), a protein that promotes directional migration by sequestering Arpin, a competitive inhibitor of the Actin-related proteins (Arp2/3) complex

CREM, cAMP-responsive element modulator alpha

This dosage fell within the effective and safe dose range (308571 mg/kg/day) determined by the weight-tiered dosing simulations of the phase 2 trial