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A cross-sectional study of 2,900 Australian men and women, 49 years of age and older, found that those in the highest quintile of riboflavin intake were 50% less likely to have cataracts than those in the lowest quintile (35)

Occasional systemic symptoms including headache, nausea, dizziness or gastrointestinal discomfort in some patients

R 1 , R 2 , and R 3 are H, R 4 is C 1-4 -alkyl and R 5 is C 1-4 -alkyl

For immunofluorescence double staining with anti-FASN and anti-8-oxo-dG, paraffin sections were incubated with rabbit anti-FASN (dilution 1:50, Cell Signaling) and mouse anti-anti-8-oxo-dG (1:250, Trevigen) at 4 C o/n in a humidified chamber