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Biosci Biotechnol Biochem 84(8):16211628 Liu J, He H, Wang J, Guo X, Lin H, Chen H, Jiang C et al (2020b) Oxidative stress-dependent frataxin inhibition mediated alcoholic hepatocytotoxicity through ferroptosis

These changes drive conversion to the pro-inflammatory M1 phenotype, which exhibits anti-tumor properties ( M2-type TAMs enhance intracellular heme accumulation by phagocytosing senescent erythrocytes