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Furthermore, the detection of fungi by culture methods depends on growth conditions and may miss uncultivable or fastidious species, while metagenomic sequencing may underrepresent fungi due to their low abundance relative to bacteria

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62,63 The low oral bioavailability of curcumin in humans is the cause for low levels of curcumin in the plasma and insufficient pharmacological effects

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Administration of EGb (40 mg/kg) and venlafaxine (15 mg/kg) reinstated BDNF expression, enhanced exploratory behavior, and lowered nNOS levels as well as stress-related physiological responses