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Nutritional factors that may be useful to consider in pain management - evidence indicates substantial relief of neuropathic pain by thiamine, pyridoxine and cyanocobalamin separately, and in combination there was a synergistic benefit, low B12 exacerbates elevated TNF- which is an inflammatory response marker

Wu X, Li J, Connolly EM, Liao X, Ouyang J, Giobbie-Hurder A, et al

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