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Follicles that have completely miniaturized or been replaced by scar tissue likely will not respond to any topical treatment

A small controlled human study did not identify a significant effect on stimulated ACTH or cortisol release

Overall, this trial was designed to precisely determine the dose-response relationship, efficacy, and safety of Cagrilintide compared with placebo and liraglutide, while employing advanced statistical methods to ensure reliable interpretation of treatment effects under both ideal and real-world adherence conditions