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In the United States alone, the economic burden of PD exceeded $52 billion in 2020, with caregivers losing an average of $19,000 in annual income due to reduced work hours or job loss (Chaudhuri et al., 2024)

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Resveratrol One of the most known polyphenols, resveratrol from the stilbene group (3,4,5-trihydroxystilbene, 5-[(E)-2-(4-hydroxyphenyl) ethenyl] benzene-1,3-diol) is a phytoalexin produced by a variety of plants and herbs in stress response

Excessive intracellular iron accumulation can lead to generation of reactive oxygen species (ROS) and oxidative stress via the Fenton reaction (Ward et al., 2014)

Metabolomics as a tool for discovery of biomarkers of autism spectrum disorder in the blood plasma of children