glutathione reductase peroxidase File:Glutathione peroxidase reductase.svg - Wikimedia

For example, in a 3-week prospective intervention with a high dose of 100 mg riboflavin/day with 70 patients with Crohns Disease, a reduction in systemic oxidative stress (measured by higher free thiol plasma levels), inflammatory markers (IL-2 and C-reactive protein (CRP)) and clinical symptoms of Crohns disease (i.e., a reduction in clinical disease activity index and quality of life improvement) were observed 52

Figures Abstract Muscle wasting is one of the main characteristics of cachexia associated with cancer and other chronic diseases and is often exacerbated by antineoplastic agents

101 , 115 (1957) Carson, P.E., Brewer, G.J., Ickes, C.: Decreased glutathione reductase with susceptibility to hemolysis

Supporting information Kumar P, Liu C, Hsu JW, et al

Nature 410 , 277284, (2001)