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Lewis, Lysine metabolism in mammals, Biochem

Mitochondrial electron transfer dysfunction further amplifies ROS production, including hydrogen peroxide (H 2 O 2) and hydroxyl radical (OH) (Sies and Jones, 2020)

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In addition, 14.7-aminoquinoline derivatives impede the Fenton reaction by Cu chelation and stimulate the Nrf2 pathway, enhancing the transcription of antioxidant enzymes, showing significant metal antagonistic properties (165, 166)

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