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It works by dissolving the cement between skin cells in the outer layer of the skin

These defects were accompanied by a significant decrease [relatively to both age-matched controls (AMC) and young adult controls (YC)] in the 2,3-DPG concentration that was accompanied by increases in the activity of diphosphoglycerate phosphatase (DPGP-ase), an enzyme that converts 2,3-DPG to 3PG (Kosenko et al., 2016)

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The plates were then incubated for 2 h at 37 C, and absorbance was measured at 450 nm using a SpectraMax i3 microplate reader (Molecular Devices, Sunnyvale, CA, USA)