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doi: 10.1016/j.aquaculture.2021.737700

This effect is thought to be mediated by the activation of adenylyl cyclase, leading to the inhibition of multiple signal transduction pathways such as ERK, JNK, and NFB

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There are six functional LOX genes (ALOX15, ALOX15B, ALOX12, ALOX12B, ALOXE3, ALOX5) in humans, which encode for six different ALOX isoforms and digits indicate oxygens introduced at the number of the carbon atom of the arachidonic acid backbone [52]