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While GHK-Cu is not a growth hormone secretagogue, it exerts potent localised effects relevant to both hair and skin: Promotion of angiogenesis , increasing capillary density around follicles Stimulation of stem cell migration and differentiation Inhibition of transforming growth factor beta (TGF-) , a cytokine associated with follicular miniaturisation Enhancement of collagen and elastin synthesis , improving scalp elasticity and barrier function Topical GHK-Cu formulations, available through Dn Research in research-grade purity, can be incorporated into routine scalp applications to directly support the hair follicle microenvironment

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As odorant degrading enzymes (ODEs), GSTs play an important role in chemoreception for the adaptation to host plant volatiles and termination of stimulation from signals (i.e., sex pheromones and plant volatiles)

A full description of the mechanism and the state of the research is expanded in a dedicated article on DSIP in the One-Peptides knowledge base