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The use of miRNAs to modulate the expression of the mutant A1AT gene and reduce the associated toxic effects has also been explored

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Three recent studies used ultra-high field strength (7T) MRS, as its greater spectral resolution and signal-to-noise ratio help to distinguish between these two metabolites

Resting astrocytes exposed to inflammatory stimuli initially adopt a transient neuroprotective state before transitioning into a sustained neurotoxic state

Ubiquinol, the reduced form of CoQ10, is often marketed as more bioavailable than ubiquinone, particularly in older adults or those with absorption issues, though both forms appear effective