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Risks of Worsening Optic Nerve Damage Theres a concern with Vitamin B12 for LHON patients

Thankamony A, Capalbo D, Marcovecchio ML, Sleigh A, Jrgensen SW, Hill NR, Mooslehner K, Yeo GSH, Bluck L, Juul A, Vaag A, Dunger DB

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The review confirmed that NNMT-mediated NAD+ depletion impairs mitochondrial function, SIRT activity (particularly SIRT1 and SIRT3), redox balance, and energy metabolism, creating conditions relevant to cardiovascular disease research models

While this delayed digestion helps reduce hunger and calorie intake, it also affects how your body absorbs certain nutrients, including vitamin B12