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In males, HCG stimulates Leydig cells to synthesize testosterone, which is critical for sperm production and male reproductive function

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In the two pivotal Phase 3 randomized, placebo-controlled trials (Study 1 and Study 2), patients treated with tesamorelin achieved a mean reduction in visceral adipose tissue (VAT) of approximately 18% in Study 1 and 14% in Study 2, compared to baseline [1], [2]

However, researchers working with 10 mg vials often target 8-10 mg as their maintenance dose, falling within the range that produced 22-24% weight loss in the trial

[DOI] [PubMed] [Google Scholar] 23.Ilic S, Brcic I, Mester M, et al