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[17] = [ | ] [ | ] = CoA } : | =6 () IUBMB Life

Frequent dosage adjustments for some immunosuppressive drugs that require therapeutic drug monitoring and dose titration based on blood concentrations, such as tacrolimus, tend to occur more often in newly transplanted recipients, and less frequently once patients are on stable regimens

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May 2007;85(5):1428-1433

Here, we report two cryo-EM structures of Ycf1 at 3.4 and 4.0 resolution in inward-facing open conformations that capture previously unobserved ordered states of the intrinsically disordered regulatory domain (R-domain)