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It should be noted, however, that H2 blockers like famotidine tend to exhibit a phenomenon known as tachyphylaxis, where the medication tends to lose its effectiveness over time. Adverse effects reported in the use of gastroesophageal reflux disease treatments in children: A 10 year literature review, British Journal of Clinical Pharmacology Famotidine, Epocrates Famotidine drug summary, Prescribers Digital Reference Famotidine tablets prescribing information, U.S

All patients will be informed that they can abandon the study at any time without this affecting their future medical treatment in any way

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Severe liver dysfunction, as the liver plays a key role in metabolizing lipotropic compounds