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[8] Novo Nordisk

[0373] Although A2-K138F had the highest binding antibody titer and second highest neutralizing antibody titer, this construct was found to form aggregates in solution, indicating potential improper protein folding, and was thus eliminated from further evaluation

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Vigorous shaking causes foaming and can lead to peptide aggregation or denaturation

Current Limitations of BPC-157 Research Although preclinical findings appear promising, researchers consistently acknowledge several important limitations