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Taking the medication with a meal may help reduce nausea

Polyphenols may have detrimental effects on the digestive systems function by impacting the composition of the intestinal flora and inhibiting digestive enzymes (602)

However, hydroxytyrosol and polyphenol extracts from extra virgin olive oil can partially reverse these detrimental effects, restoring NO levels and reducing ET-1 synthesis (Storniolo et al., 2014)

(iii) Mito-TEMPO (#sc-221945, Santa Cruz, Dallas, Texas, USA) was dissolved in DMSO at a concentration of 10 mM and diluted to the final concentration of 1 M directly in culture medium