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This imbalance contributes to the increased permeability of the gut barrier, allowing the translocation of harmful bacterial products (such as lipopolysaccharides (LPS)) into the bloodstream, where they can activate the brains immune system and promote neuroinflammation, which is a major contributor to cognitive dysfunction (Guerville and Boudry, 2016

The method of claim 17, wherein isolating the propionyl-L-carnitine nitrate comprises crystallizing the propionyl-L-carnitine nitrate by drying the reaction between the propionyl-L-carnitine free base and nitric acid

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Diets like the Mediterranean Diet (MedDiet), which have a low omega-6 to omega-3 ratio, have been found to reduce the risk of Alzheimer's disease (AD) and slow down cognitive decline (253)