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Repression of Stress-Induced LINE-1 Expression Protects Cancer Cell Subpopulations From Lethal Drug Exposure

Notably, the azo-containing chemotherapeutic drug procarbazine for the treatment of Hodgkins lymphoma and brain cancers was found to interact through a similar mechanism of action involving the transformation of GSH to GSSG and regeneration of the catalyst through a reaction with O 2 38,39 , providing feasibility of the proposed catalysis