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97,123 In vitro, AST IV suppressed T follicular helper cell responses, expanded T follicular regulatory cell responses, and regulated the Notch signaling pathway, thereby reversing remodeling progression

Interestingly, recent mouse studies indicate that apoE impacts on A plaque initiation since suppression of apoE expression using antisense oligonucleotides (ASOs) in AD transgenic mice reduced plaque load only when delivered prior to plaque onset but had no effect once the plaques were established [165]

Children with Down syndrome have abnormal metabolic profiles and show increased incidence of a large number of serious diseases including leukemia and diabetes [61]

Bu D, Luo H et al (2021) KOBAS-I: intelligent prioritization and exploratory visualization of biological functions for gene enrichment analysis