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HHcy generally correlated with cumulative LDopa dose without significant association with vitamin levels (Mancini et al

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Savarimuthu FSM, Larsen JE, Pavey SJ, Duhig EE, Clarke BE, Bowman RV, Hayward NK, Fong KM, Yang IA (2011) Genes and gene ontologies common to airflow obstruction and emphysema in the lungs of patients with COPD

Folate insufficiency was one of these three variables that had the most impact on the serum tHcy levels, followed by MTHFR C677T and vitamin B12 deficiency (in decreasing order of impact) [48]

NeuroImage 59:26782688 Buschmann JP, Berger K, Awad H, Clarner T, Beyer C, Kipp M (2012) Inflammatory response and chemokine expression in the white matter corpus callosum and gray matter cortex region during cuprizone-induced demyelination