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The decreased concentration of DA as well as increased DOPAC, a principal metabolite of DA, reflects increased breakdown as well as turnover of dopamine

Ursodeoxycholic acid versus placebo in the treatment of women with intrahepatic cholestasis of pregnancy (ICP) to improve perinatal outcomes: protocol for a randomised controlled trial (PITCHES)

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These encompass the maintenance of iron homeostasis, the metabolic process of cysteine, the activity of GPX4, the synthesis of polyunsaturated fatty acids (PUFA), the regulatory role of nuclear factor E2-related factor (NRF2), the function of the tumor suppressor protein p53, the protective mechanism of heat shock proteins (HSPs), the regulatory role of iron regulatory inhibitor-1 (FSP1), the activation state of AMP-activated protein kinase (AMPK), and the supply of nicotinamide adenine dinucleotide phosphate (NADPH)

011 ) and a statistical trend for the main effect of baseline HOMA-IR HOMA-IR ( F(1 , 185) = 2