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Statements Author contributions CG, SiS, TA, and TK wrote the manuscript, reviewed the literature, and collected the information

Several studies indicate that hypoxia can increase mitochondrial fission in various cell types by upregulating Dynamin-related protein 1 (Drp1) activity through HIF1 (Table 1)

Kersten K, de Visser KE, van Miltenburg MH, Jonkers J

Tang and Ginsburg, 2023)

A trimer of Leukotriene C4 synthase is localized on the outer nuclear membrane and endoplasmic reticulum, where it forms a complex with 5-Lipoxygenase-activating protein