methotrexate glutathione Synthesis of glutathione-responsive, amphiphilic methotrexate-based prodrug nanoparticles: In vitro and in vivo assessment against metastatic breast cancer Busting the myth of methotrexate

[DOI] [PubMed] [Google Scholar] O'Reilly BA, Warning RH

Since N0362 binds to CXCR1 with high affinity, we speculated that it may function as an antagonist of IL-8 and prevent it from binding to CXCR1, thereby blocking neutrophils chemotaxis

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Westerhof, N., Stergiopulos, N., Noble, M

Sun C, Seranova E, Cohen MA, Chipara M, Roberts J, Astuti D, Palhegyi AM, Acharjee A, Sedlackova L, Kataura T, Otten EG, Panda PK, Lara-Reyna S, Korsgen ME, Kauffman KJ, Huerta-Uribe A, Zatyka M, Silva L, Torresi J, Zhang S, Hughes GW, Ward C, Kuechler ER, Cartwright D, Trushin S, Trushina E, Sahay G, Buganim Y, Lavery GG, Gsponer J, Anderson DG, Frickel EM, Rosenstock TR, Barrett T, Maddocks ODK, Tennant DA, Wang H, Jaenisch R, Korolchuk VI, Sarkar S