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10 Conclusions Despite numerous research studies and resources invested, the question of what determines the transition from pharyngeal colonization to IMD, which has been raised since Weichselbaums meningococcus, the main agent of epidemic cerebrospinal meningitis, was identified (Weichselbaum, 1887), remains without a definitive answer

McCoy et al., Journal of Pharmacology and Experimental Therapeutics (2013) Foundational research examining the biochemical and cellular mechanisms of Dihexa in cell signalling and neurobiological contexts

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a neurotoxin that causes dopaminergic neurodegeneration and mitochondrial deficiency reminiscent of Parkinsons disease

Tirzepatide is engineered as a single molecule that activates both receptors rather than being two separate medications combined

For ROS detection, liquid dihydroethidium (DHE) was utilized (Beyotime, Shanghai, China, S0033S)