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Abbreviations AA : Amino acid ANOVA : Analysis of variance AUC : Area under the curve BCAA : Branched-chain amino acid BMI : Body mass index ESI : Electrospray ionization IFP : Infrapatellar fat pad KOA : Knee osteoarthritis LDA : Linear discriminant analysis LI : Level of identification OA : Osteoarthritis PLS-DA : Partial least squares discriminant analysis QC : Quality control RA : Rheumatoid arthritis ROC : Receiver operating characteristic SE : Standard error SF : Synovial fluid TKA : Total knee arthroplasty TOF : Time-of-flight VIP : Variable importance in projection References Kontny E, Zieliska A, Ksiopolska-Orowska K, Guszko P (2016) Secretory activity of subcutaneous abdominal adipose tissue in male patients with rheumatoid arthritis and osteoarthritis association with clinical and laboratory data

Epidemiology 10:370375

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Rather than running each compound separately, investigators studying joint stress, tendon overload, or wound-repair models can work from a single pre-verified formulation with documented purity across all four components

They are particularly beneficial for dry or mature skin types