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The cGAS-STING pathway is a major cytosolic DNA-sensing pathway, where cGAS detects foreign DNA and synthesizes cyclic GMP-AMP, which then binds to and activates STING

A., Eryilmaz, R., Demir, H., Aykan, S

Cyclin D1 promotes the progression of the G1S phase, and tamoxifen can reduce the expression of cyclin D1, which is highly expressed in drug-resistant cells (Viedma-Rodriguez et al., 2014)

Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase

It encourages the production of telomerase, an enzyme that repairs and extends telomeres, supporting healthier cell replication