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EXAMPLE 13: CONFIRMATION ON THE EFFECT OF TONICITY AGENT TYPE IN THE HISTIDINE-BUFFERED FORMULATION AND THE EFFECT OF THE CITRATE- BUFFERED FORMULATION ON THE SUBCUTANEOUS TOLERANCE UPON SUBCUTANEOUS INJECTION This experiment examines: (1) the effect that the type of tonicity agent has on the local tolerance profile, upon subcutaneous injection, of an otherwise identical, histidine-buffered co-formulation

Oral no reconstitution needed Frequency: daily for 20 days (one full vial per day), 2 to 3 cycles per year

[DOI] [PubMed] [Google Scholar] 28.Hu Q., Corral P., Narayanapillai S.C., Leitzman P., Upadhyaya P., OSullivan M.G., Hecht S.S., Lu J., Xing C

Localized heat sent to the source means tolerable temperatures and a quicker, deeper sweat