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Idiopathic guttate hypomelanosis is usually a clinical diagnosis

Thus, the IGF-1 signaling is essential for processes such as cell proliferation, survival, and metabolic regulation, impacting various organs and systems

They showed extensive cutaneous hyperpigmentation in previously unaffected skin, probably induced by doxycycline

It sets narrow and flawed diagnostic criteria and unfortunately set the tone for the following GP audits and it still largely influences diagnosis today

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