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Gao X, Lee K, Reid MA, Sanderson SM, Qiu C, Li S, et al

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intraperitoneal injection of 10 mg/kg [125], drinking water with 25 mM for 1 weeks [158], and dietary supplementation with 1000 ppm for 2 weeks [159]) effectively increased pancreatic MT levels and provided protective outcomes in rats and mice with STZ-induced diabetes, with results ranging from moderate to significant protection

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A standardized data extraction form was used to collect the following information: first author, year of publication, sample size, type and dosage of the antioxidant intervention, duration of treatment, altitude of exposure, physiological variables, oxidative stress biomarkers, and clinical outcomes defined during exposure to hypobaric hypoxia

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