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BSO-treated rats had a lower probability to reach a high breakpoint (Supplementary Figure 3e) and a non-significant tendency to perform fewer nosepokes (Supplementary Figure 3f) than the DMSO group

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Leist M, Single B, Castoldi AF, Khnle S, Nicotera P

Association of the metabolic syndrome with history of myocardial infarction and stroke in the Third National Health and Nutrition Examination Survey

Moreover, high glucose levels activate the NLRP3 inflammasome, promoting pyroptosis and disrupting estradiol synthesis (Xu R