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Briefly, all information related to LDX was searched in PubMed (USA National Library of Medicine) without a limiting period regarding the historical background, chemical aspects, formulations, pharmacokinetics, pharmacodynamics, as well as its usefulness, clinical efficacy and adverse effects inherent to its exposure

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This arm of the mechanism is also believed to drive PCSK9 degradation, which appears to lower LDL cholesterol in clinical readouts

External fatty acid standards (Sigma-Aldrich Chemical Company) were used to identify components