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First, 3-phosphoglycerate is oxidized to 3-phosphohydroxypyruvate with concomitant production of NADH, catalyzed by phosphoglycerate dehydrogenase (PHGDH)

Evidence suggests that solute carrier family 25 member 10 (SLC25A10) mediates the import of cytosolic GSH into mitochondria to prevent iron deposition-induced myocardial ferroptosis, a process regulated by the Nrf2/MPV17 axis, which also restores mitochondrial respiratory chain activity and may exert beneficial effects on cardiac function in MIRI [144]

Itch E3 ligase-mediated regulation of TGF-beta signaling by modulating smad2 phosphorylation

Chinese Medical Journal Pulmonary and Critical Care Medicine

Biodistribution and Efficacy of L-Annamycin in a Novel Imageable AML Mouse Model