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Besides these roles, GSH also plays role in detoxification of methylglyoxal, formation of phytochelatins, interacts with plant hormones, other signaling molecules and its redox state triggers signal transduction, and also acts as a cofactor in several biochemical reactions

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HUVECs and NIH 3T3 cells in Roswell Park Memorial Institute (RPMI) 1640 and HaCaT in Dulbeccos Minimum Essential Medium (DMEM)/F-12 medium were cultured in the indicated media supplemented with 10% fetal bovine serum (FBS) and maintained at 37C in a humidified environment with 5% CO 2

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In addition, 61.2% (90/147) of the downregulated proteins were assigned to catalytic activity

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