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Studies have shown that nicotine may upregulate matrix metalloproteinases (MMPs) expression by activating 42 nAChRs

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Cell 149:10601072 Dron M, Clouse SD, Dixon RA, Lawton MA, Lamb CJ (1988) Glutathione and fungal elicitor regulation of a plant defense gene promoter in electroporated protoplasts

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Meanwhile, the NAC + BSO administration decreased the high level of GSH caused by Notch2 over-expression

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