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There is a theoretical concern (and some limited clinical evidence) that high-dose antioxidants like ALA could reduce the efficacy of these treatments

There are notable differences in general disease characteristics such as the faster progression rate in EOAD with more frontotemporal atrophy rather than hippocampal atrophy in LOAD and primarily poorer executive, motor and visuospatial functions in comparison to the primarily poorer memory evident in LOAD (Tellechea et al., 2018)

Store at room temperature in a clean, dry environment away from direct sunlight

Used carelessly, they're a gamble

However, if your skin appears dull or has uneven pigmentation, brightness may be your first priority