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As noted above, SOD1/2 (Cu/Zn and Mn, respectively), CAT, and GPx catalyze the dismutation of O to O 2 and H 2 O 2 and the subsequent decomposition of the latter to O 2 and H 2 O

Experiments were carried out C6 astroglioma cells, a cellular model which recapitulates astrocytes features ( We found here that in C6 cells GSH depletion exacerbates store-operated calcium entry (SOCE) mechanism triggered by IP 3 -mediated Ca 2+ release