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The defects arise from failure of the embryonic neural tube to close, which occurs between the 21st and 28th days after conception, a time when most women are unaware of their pregnancy (57)

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The investigators reported that oral AOD-9604 administration in rodent models produced measurable increases in fat oxidation and reductions in body fat, and that direct application of the compound to ex vivo human adipose tissue produced concentration-dependent increases in lipolysis [2]

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