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The distribution coefficients in octanol-phosphate buffered saline indicated the highly hydrophilic nature of GHK-Cu with log D values between 2.38 and 2.49 at a pH range of 4.57.4

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Disclosure of interest: FAM, KG, VR, MK, WNW, KB, PH have nothing to disclose Poster Session I - RISK FACTORS - PRIMARY AND SECONDAR PREVENTION 05.00 - RISK FACTORS AND PREVENTION (PRIMARY AND SECONDARY) - 05.01 - PREVENTION P405 - ESOC25-1791 THE IMPACT OF FRAILTY ON STROKE RISK IN ELDERLY PATIENTS WITH ATRIAL FIBRILLATION Natalie Burgos Bencosme 1 , Sarah Rodrguez Santiago 1 , Lucia Antua Montes 1 , Elena Valle Calongue 1 , German Guzman Gutierrez 2 , Sara Fueyo lvarez 1 , Julieth Caballero Velsquez 1 , Eva Lopez Alvarez 1 , Jos Gutirrez Rodrguez 1 , Monserrat Gonzlez Delgado 3 , Jorge Herrera Parra 1 1 Monte Naranco Hospital, Oviedo, Spain, 2 University of Aberdeen-NHS Grampian, Aberdeen, United Kingdom, 3 Central University Hospital of Asturias, Oviedo, Spain Background and Aims: In the context of an ageing population, understanding how elderly individuals with atrial fibrillation (AF) characteristics influence stroke incidence is crucial

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